Authentication of saussurea lappa, an endangered medicinal material. Alantolactone from saussurea lappa exerts antiinflammatory effects by inhibiting chemokine production and stat1. Saussurea, also called saussurea lappa, sea costus and kushta, is a pungent tasting medicinal herb native to south asia. This study was performed to investigate the potential use of saussurea lappa c. It is endangered species which is controlled by the ministry of environment and forest. In addition, inappropriate use wrong plant parts, dose, frequency, route of administration, preparation, etc. Despite significant progress in phytochemical and biological analyses of s. Saussurea lappaextract was prepared by maceration of 50 gm of saussurea lapparoots with 90% methanol, then chemical detection of flavonoids, alkaloids, tannins, saponins, terpenes and steroids was carried out. Kushta, indian costus root saussurea lappa properties. Costus root is used for treating worm nematode infections. Clarke is a wellknown and important medicinal plant widely used in several medicinal systems for the treatment of various diseases, viz. It is widely used in the treatment of asthma, ulcer, stomach problems and. Saussurea synonyms, saussurea pronunciation, saussurea translation, english dictionary definition of saussurea. The root and oil from the root are used to make medicine.
Its medicinal properties are well documented in traditional chinese medicine, the tibetan system of medicine, and ayurvedic medicine. Saussurea costus synonyms, saussurea costus antonyms. The test conducted on mice shows that saussurea costus treatment helps to lower liver damage related with hepatitis. About 25% of these are herbal extract, 22% are crude medicine, and 2% are prepared drugs in pieces. Other than medicinal purposes its oil is also used as a flavoring component.
Saussurea costus is the only common medicinal herb listed in. Saussurea costus is the only common medicinal herb listed in appendix i critically endangered of the cites index. Phytochemistry of saussurea lappa after thorough literature survey revealed various varied and copious metabolites such as sesquiterpenes, flavonoids, phytosterols, lignans, terpenes. Asteraceae, costus, export, himalaya, india, medicinal plant, wild.
Saussurea lappa is generally regarded as safe gras by the u. Conservation status and therapeutic potential of saussurea. Practical uses of saussurea lappa it is effective remedy against foul smell, chronic ulcers, headache, toothache, synovitis, rheumatoid arthritis and dermatitis as a poultice or fumigation. Aqueous extract of saussurea lappa root ameliorate oxidative. Conservation status and therapeutic potential of saussurea lappa. Mesopotamia provide the evidence of the use of medicinal herbs by. Common side effects may include dizziness and nausea. Saussurea lappa clarke compositae is a traditionally known and potent plant which is well considered for its medicinal uses in different indigenous indian systems of medicine. Saussurea lappa is used a component of the traditional tibetan medicine padma 28. Antiulcerogenic activity of saussurea lappa root niranjan sutar, ranju garai, uma shankar sharma, narendra singh and saumendu deb roy department of pharmacy, sir madanlal group of institutions, etawah, upindia abstract the study was designed to investigate the antiulcer activity of ethyl acetate extract of the saussurea lappa root using. The plant saussurea lappa is commonly known as costus. The taxonomy of the genus saussurea in this treatment follows largely the monograph by lipschitz rod saussurea, 1284. Saussurea lappa, biological active compounds, medicinal uses. Saussurea lappa is one of the most common prescribed herbs in indigenous systems of medicines in china, tibet and india for treatment of various types of human ailments such as fever, bronchitis, rheumatoid arthritis, typhoid fever and chronic skin diseases.
Two new guaianetype sesquiterpene lactones with an unusual sulfonic acid group, sulfocostunolide a 1 and sulfocostunolide b 2, were isolated from the roots of saussurea lappa. It is also used as a tonic and to stimulate digestion in foods and beverages, costus oil is used as a flavoring component. Essential oils are extracted from its roots which are used to treat various ailments. Saussurea definition of saussurea by medical dictionary.
Mu xiang, kuth, costus saussurea lappa decne, aucklandia lappa, aplotaxis lappa decne, saussurea costus culture. Saussurea lappa annual herb of the eastern himalayas having purple florets and a fragrant root that yields a volatile oil used in perfumery and. Saussurea lappa was used in the treatment of dental diseases as it is effective against cariesinducing streptococcus mutans4. Saussurea as an ayurvedic medicine benefits, dosage and. Saussurea is a member of the daisy family and may cause allergy in people allergic to artichoke, asters, common burdock, cosmos. Also there has been a tremendous interest in this plant as evidenced by the voluminous work carried. Medicinal uses costi amari radix or costus root was an important item of roman trade with india, and is believed to have been the dried root of saussurea lappa. Kala reveals that the practitioners of tibetan medicine living in the pin valley of himachal pradesh use its root for curing dysentery and ulcer.
Clarke is a well known and important medicinal plant widely used in several indigenoussystemsofmedicineforthetreatmentofvariousailments,viz. Comparative study of inula racemosa and saussurea lappa on. Saussurea lappa definition of saussurea lappa by the. Saussurea genus of herbs of temperate and cool regions of eurasia genus saussurea asterid dicot genus genus of more or less advanced. Based on article 16d1, article 16f and article 16h of directive 200183ec as amended traditional use final herbal substances binomial scientific name of the plant, including plant part arctium lappa. Saussurea definition of saussurea by the free dictionary. Uses, side effects, interactions, dosage, and warning. This plant is found extensively in sub himalayan regions along the sides of rivers. Saussurea costus is effective as a treatment for cough, asthma, bronchitis and cholera. Presence of cholinergic and calcium antagonist constituents in saussurea lappa explains its use in constipation and spasm. Kushta is good appetizer, digestive and carminative i. Although callusfree multiple shoots were obtained both on n6benzyladenine ba.
Micropropagation through apical shoot explants and. Costus is a commonly used medicinal herb in china and is considered to be one of their 50 fundamental herbs. Clarke asteraceae introduction saussurea dc is a large genus of annual, biennial or perennial herbs distributed in the temperate regions of asia, europe and north america. For ages together, this ancient plant has been used to heal the human body.
It is in flower from july to august, and the seeds ripen from august to september. A wide variety of saussurea lappa options are available to you, such as supply type, raw material, and packaging. Saussurea lappa is also used as an alternative, allnatural holistic remedy to treat chronic persistent hepatitis and anicteric hepatitis. It is also used in ayurvedic medicine where it is valued. It is popularly known as kuth root or costus and used in various traditional system of medicine for its antiulcer, anticonvulsant, anticancer, hepatoprotective, antiarthritic, antiviral activities.
Tripathi department of medicinal chemistry, institute of medical sciences, banaras hindu university, varanasi 221 005, india. Many of these compounds have been found to possess a wide range of biological activity such as anticancer, antiinflammatory, antihepatotoxic, antiviral, etc. Committee on herbal medicinal products hmpc assessment report on arctium lappa l. The species is hermaphrodite has both male and female organs and is pollinated by insects. In the present study, we investigated the antiinflammatory effects of saussurea lappa, a medicinal herb, and its marker compounds alantolactone. Saussurea lappa, acacia nilotica, ricinus communis, antibacterial activity, agar diffusion assay 1. The use of high performance liquid chromatography technique helped in detection of querciten, rutin, myricetin and kaempferol, luteolin. Callus free multiple shoots were attained on media supplemented with. Saussurea article about saussurea by the free dictionary.
The hexane extract of saussurea lappa and its active principle, dehydrocostus lactone, inhibit prostate cancer cell migration, journal of medicinal food, vol. The family has 300 species globally in which approximately 61 species exist in india 2. It is also used as a tonic and to stimulate digestion. Research conducted on the himalayan medicinal plants by c.
The plant bears big serrated leaves and its roots are being used for medicinal purposes. The inhibitory effects of saussurea lappa in ethanol extract on the growth of streptococcus mutans in a dose dependent manner was recorded3. It can reach up to two meter in length and creeps on the ground. Rapid in vitro propagation of saussurea lappa, an endangered. Alantolactone from saussurea lappa exerts antiinflammatory. The effect of antiinflammatory and antimicrobial herbal remedy padma 28 on immunological angiogenesis and granulocytes activity in mice. Clarke has been used in folk medicine for the treatment of. Special attention is required for the sustainable use of natural resources and also attention for the conservation of environment in the moist temperate himalaya region of pakistan 9.
Aucklandia, also known as costus or mu xiang, is the root of the plant saussurea costus. Out of 125 species about 47 species are reported in india of which saussurea lappa is reputed for the medicinal properties of its roots. Saussurea costus is a perennial growing to 3 m 9ft by 1 m 3ft 3in. The root of the plant is the key part used for medicinal or homeopathic purposes. Rapid in vitro propagation of saussurea lappa, an endangered medicinal. Traditionally used in india as an aphrodisiac, tonic, stimulant, and antiseptic. List of medicinal and aromatic plants our company supplies a variety of fresh and genuine herbs as per customers demand. Kushta saussurea lappa benefits, usage, dose, side effects kushta or indian costus root is a famous ayurvedic herb used in treating gout, skin diseases, respiratory disorders etc. Saussurea lappa is a traditionally wellknown plant for its medicinal uses in different indigenous systems of medicine. Dpph is a stable free radical that accepts an electron or hydrogen radical.
Prophylactic effect of cousts saussurea lappa against liver injury. Saussurea lappa synonyms, saussurea lappa pronunciation, saussurea lappa translation, english dictionary definition of saussurea lappa. Saussurea costus common name is costus and local name is kuth. They have been reported for their wide spectrum of biological effects, including antiinflammatory, anticancer, antiviral, antimicrobial, antifungal, antioxidant, antidiabetic, antiulcer, and anthelmintic activities. Food and drug administration fda when used as a dietary supplement. Saussurea is a genus of about 300 species of flowering plants in the thistle tribe within the. Saussurea costus is beneficial for treating liver ailments according to the study conducted on animals. In china, the hengduan shan area is the center of diversity of saussurea, with more than one hundred species, many of them endemic. Comparative study of inula racemosa and saussurea lappa on the glucose level in albino rats p. The root of saussurea lappa is mainly used for medicinal purposes. Another padma 28 component, saussurea lappa root, and its active principle dehydrocostus lactone inhibit prostate cancer cell migration in vitro and have been shown to have anticancer activity.
Costus oil is used for asthma, cough, gas, and severe intestinal diseases such as dysentery and cholera. Pdf saussurea lappa clarke compositae is a traditionally known and potent plant which is well considered for its medicinal uses in different. Costusbased formulas also treat diarrheapredominant ibsd irritable bowel syndrome, peptic ulcers, flatulence, colic, bacillary dysentery, infantile enteritis, and cholecystitis. Nanda medicinal plants company is registered with ministry of environment and forest for cultivation of threaten species. Their structures were elucidated on the basis of extensive spectroscopic analysis.